Gastroenterology
Upper and lower gastrointestinal bleeding
Written 30 September 2026.
Why this matters
The color of the blood matters less than whether the patient is shocked.
Rapid clinical summary
- Resuscitate before you negotiate an elective endoscopy.
- Hematemesis and melaena are upper until proved otherwise. Fresh red blood per rectum can still be a brisk upper bleed.
- A transfusion target is protocol-specific. It is not printed here.
Mechanism
Blood leaves the gut faster than it can be replaced. Portal hypertension, ulcer, and mucosal disease are different sources with different definitive treatments, but shock looks the same at the door.
Recognition
Shock plus gastrointestinal blood is a resuscitation problem first.
Typical
- Hematemesis
- Melaena
- Hematochezia
- A liver history
- Antiplatelet or anticoagulant drugs
Red flags
- Hypotension
- Tachycardia
- Confusion
- Ongoing hematemesis
- A suspected variceal source
Differential
| Condition | Clue | Trap |
|---|---|---|
| Peptic ulcer | Pain, an anti-inflammatory drug | Assuming every bleed is variceal |
| Varices | Known cirrhosis, signs of chronic liver disease | A routine outpatient endoscopy |
| Diverticular lower bleed | Large-volume fresh blood, older adult, hemodynamics may still fail | Forgetting that brisk upper bleeding can look the same |
Investigations
- Hemoglobin lags behind acute loss. Do not wait for anemia to believe a shocked patient.
- Endoscopy after resuscitation, with the timing set by stability and the likely source.
Management
- Immediate
- Airway if vomiting blood and consciousness is falling. Two points of access, blood bank, and reversal of anticoagulation according to the local protocol.
- Definitive
- Endoscopic, radiological, or surgical hemostasis depending on the source. Variceal and ulcer pathways are not the same. Drugs are not dosed on this page.
- Monitoring
- Pulse, blood pressure, and whether bleeding is continuing. A single ‘stable’ set of observations during a pause is not a cure.
Common pitfalls
- Sending ongoing hematemesis to a clinic.
- Using the hemoglobin alone to judge acute loss.
- One protocol for varices and ulcers.
Exam reasoning
The next step in a hypotensive patient is resuscitation, not a booking.
Practice this topicOpens original Mahazanaka questions in this subject. If this subject is thin on that track, the session uses what exists.
Visual summary
Endoscopy follows resuscitation.
Recognize, reason, prioritize, act safely
- Recognize. Blood from the gut, and the vital signs.
- Reason. Upper or lower, variceal or not, still bleeding or not.
- Prioritize. Airway and circulation before the camera.
- Act safely. Resuscitate, then the hemostatic procedure.
Knowledge check
Ongoing hematemesis and blood pressure 80/50. What comes before a routine endoscopy slot?
No citation is attached to this chapter. Nothing here is personal medical advice.
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