Respiratory
Pulmonary embolism
Written 30 September 2026.
Why this matters
Clot in the lung is easy to under-call in a stable patient and easy to over-treat in the wrong patient.
Rapid clinical summary
- Sudden dyspnea, pleuritic pain, and a risk factor belong on the list.
- Shock or collapse is an emergency resuscitation problem, not an outpatient score.
- A stable patient needs a confirmatory pathway, not automatic thrombolysis.
Mechanism
Embolus blocks pulmonary arteries. Dead space rises. Blood is redirected through the remaining lung, which can lower oxygenation. A large clot obstructs the right ventricle.
Recognition
Ask two questions: could this be clot, and is the right ventricle failing now?
Typical
- Sudden breathlessness
- Pleuritic pain
- Cough, sometimes blood
- A swollen leg
- Recent immobility or surgery
Red flags
- Syncope or collapse
- Hypotension
- Hypoxia
- A raised jugular venous pressure with a clear chest
Differential
| Condition | Clue | Trap |
|---|---|---|
| Pneumonia | Fever, focal crackles, sputum | Every infiltrate is not clot, and every clot is not pneumonia |
| Pneumothorax | Absent sounds on one side | Skipping the examination |
| ACS | Pressure pain, ECG change | The two can coexist after surgery. Do not force one label |
Investigations
- Unstable: resuscitate. Imaging is chosen by the emergency pathway, not by a clinic algorithm.
- Stable: probability, then a test that can confirm. A D-dimer is not a way to discharge shock.
Management
- Immediate
- Oxygen if hypoxic, support of blood pressure if shocked, and a senior emergency decision about reperfusion when massive embolism is the working diagnosis.
- Definitive
- Anticoagulation when embolism is confirmed or when the probability is high enough that waiting is unsafe. The drug and dose are protocol-specific and are not on this page.
- Monitoring
- Bleeding, recurrence of shock, and the reason the clot happened.
Common pitfalls
- Sending a shocked postoperative patient home for a later D-dimer.
- Thrombolysing a stable patient because the story is classic.
- Forgetting bleeding risk when anticoagulation starts.
Exam reasoning
The discriminator is blood pressure and perfusion, not how dramatic the history sounds.
Practice this topicOpens original Mahazanaka questions in this subject. If this subject is thin on that track, the session uses what exists.
Visual summary
Shock changes the pathway.
Recognize, reason, prioritize, act safely
- Recognize. Sudden dyspnea plus a risk.
- Reason. Is this massive, or is there time to confirm?
- Prioritize. Resuscitation before a probability essay.
- Act safely. Match the step to stability.
Knowledge check
Day 6 after surgery, collapse, blood pressure 78/46. Is an outpatient D-dimer the right plan?
No citation is attached to this chapter. Nothing here is personal medical advice.