Medicine Library

Respiratory

Pulmonary embolism

Written 30 September 2026.

Why this matters

Clot in the lung is easy to under-call in a stable patient and easy to over-treat in the wrong patient.

Rapid clinical summary

  • Sudden dyspnea, pleuritic pain, and a risk factor belong on the list.
  • Shock or collapse is an emergency resuscitation problem, not an outpatient score.
  • A stable patient needs a confirmatory pathway, not automatic thrombolysis.

Mechanism

Embolus blocks pulmonary arteries. Dead space rises. Blood is redirected through the remaining lung, which can lower oxygenation. A large clot obstructs the right ventricle.

Recognition

Ask two questions: could this be clot, and is the right ventricle failing now?

Typical

  • Sudden breathlessness
  • Pleuritic pain
  • Cough, sometimes blood
  • A swollen leg
  • Recent immobility or surgery

Red flags

  • Syncope or collapse
  • Hypotension
  • Hypoxia
  • A raised jugular venous pressure with a clear chest

Differential

ConditionClueTrap
PneumoniaFever, focal crackles, sputumEvery infiltrate is not clot, and every clot is not pneumonia
PneumothoraxAbsent sounds on one sideSkipping the examination
ACSPressure pain, ECG changeThe two can coexist after surgery. Do not force one label

Investigations

  • Unstable: resuscitate. Imaging is chosen by the emergency pathway, not by a clinic algorithm.
  • Stable: probability, then a test that can confirm. A D-dimer is not a way to discharge shock.

Management

Immediate
Oxygen if hypoxic, support of blood pressure if shocked, and a senior emergency decision about reperfusion when massive embolism is the working diagnosis.
Definitive
Anticoagulation when embolism is confirmed or when the probability is high enough that waiting is unsafe. The drug and dose are protocol-specific and are not on this page.
Monitoring
Bleeding, recurrence of shock, and the reason the clot happened.

Common pitfalls

  • Sending a shocked postoperative patient home for a later D-dimer.
  • Thrombolysing a stable patient because the story is classic.
  • Forgetting bleeding risk when anticoagulation starts.

Exam reasoning

The discriminator is blood pressure and perfusion, not how dramatic the history sounds.

Practice this topic

Opens original Mahazanaka questions in this subject. If this subject is thin on that track, the session uses what exists.

Visual summary

Embolism and blood pressure

Shock changes the pathway.

Embolism and blood pressureSudden dyspneaShock?ResuscitateOr confirm

Recognize, reason, prioritize, act safely

  1. Recognize. Sudden dyspnea plus a risk.
  2. Reason. Is this massive, or is there time to confirm?
  3. Prioritize. Resuscitation before a probability essay.
  4. Act safely. Match the step to stability.

Knowledge check

  • Day 6 after surgery, collapse, blood pressure 78/46. Is an outpatient D-dimer the right plan?

No citation is attached to this chapter. Nothing here is personal medical advice.